Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

DG DISPATCH - AAN: Metifronate Improves Psychiatric Profile Of Patients With Alzheimer’s Disease By Cameron Johnston Special to DG news TORONTO, ON -- April 26, 1999 -- Patients with Alzheimer’s disease who take metifronate appear to have fewer psychiatric symptoms than Alzheimer’s patients who do not receive the drug, researchers from University of California Los Angeles (UCLA) Alzheimer’s Disease Center reported this week at the American Academy of Neurology meeting in Toronto. Studies involving other drugs to treat the disease have shown that the patient does not suffer as much cognitive impairment, but this is the first study that has shown changes in the patient’s eating habits and moods while they are taking the experimental drug. In the study, 830 non-institutionalized patients with mild to moderate to moderate Alzheimer’s disease received either 50 mg or 60-80 mg daily over a period of 26 weeks. Using an Alzheimer’s Disease Assessment Scale (ADAS-noncog) the patients experienced statistically significant improvements in their degree of distractibility, hallucinations, motor function and appetite. The only domain in which the patients did not show an improvement was in their tendency to break down crying from time to time, said Donna Masterman, a UCLA researcher. The fact that they seemed to experience an improvement in appetite is also important she said, because loss of appetite and poor eating habits are often warning signs that a person is losing the ability to care for himself or herself. Poor eating habits may also leave the patients susceptible to other illnesses. The appetite scores in this study suggest that these patients could possibly go on living on their own, outside nursing homes or hospitals, without the need for an outside person to prepare their meals. E-mail this page to a friend or colleague! To print, use this version