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Prophylactic Mastectomy Reduces Breast Cancer Risk By Almost 90% ROCHESTER, MN -- Jan. 13, 1999 -- A Mayo Clinic study has identified new information that will allow women at risk for breast cancer, especially those at high risk, to make more informed decisions with their physicians about possible courses of preventive action. The study, to be published in tomorrow’s edition of the New England Journal of Medicine, finds that prophylactic mastectomy, surgery that removes the breasts as a preventive measure, reduces the risk of breast cancer by approximately 90 percent for women at moderate to high risk for the disease. Breast cancer affects one in nine women in the United States during their lifetimes and five percent to 10 percent of breast cancers occur in women with an inherited risk for the disease. E-mail this page to a friend or colleague! To print, use this version