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| |  Research Collaboration in the Field of Diabetes Care BAGSVAERD, Denmark, Oct. 29, 1996 -- Novo Nordisk A/S (NYSE: NVO) today announced that a research collaboration has been signed with Takeda Chemical Industries, Ltd. in the field of Diabetes Care. The aim of the collaboration is to identify compounds that may potentially be developed into orally active drugs to control blood glucose levels in people with Type 2 diabetes. Joint research will be based on Novo Nordisk's extensive expertise related to the cell receptors responsible for blood glucose regulation combined with Takeda's library of small organic molecules with specific affinity for these receptors. The research program will be co-operative and costs will be split equally between the two companies. No up-front payment or milestone payments are involved. Mads Krogsgaard Thomsen, corporate vice president, Health Care Discovery, Novo Nordisk, said, "The research agreement is very important because the combined forces of Novo Nordisk and Takeda increase our chances of using our proprietary technology to develop new and better drugs to treat Type 2 diabetes." Novo Nordisk A/S is the world leader in insulin and diabetes care and also manufactures and markets a variety of other pharmaceutical products. Furthermore the company is the world's largest producer of industrial enzymes. Headquartered in Denmark, Novo Nordisk employs approximately 13,400 people in 54 countries and markets its products in 130 countries. Its B shares are listed on the stock exchanges in Copenhagen, London and Zurich. Its ADSs are listed on the New York Stock Exchange under the symbol "NVO." Takeda Chemical Industries, Ltd. is Japan's leading pharmaceutical company. The company's R&D-oriented activities encompass every major sector of prescription pharmaceuticals and an expanding range of OTC products. Further, Takeda enjoys a strong reputation as the world's leading manufacturer of bulk vitamins and boasts a solid lineup of food products and ingredients; chemical products; agricultural chemicals; and animal health products as well as environmental products. The company also has numerous subsidiaries and affiliates that comprise a dynamic R&D, production, and marketing network, spanning Asia, Europe, and North America.
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