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Zyprexa Cleared for Marketing in European Union for Schizophrenia INDIANAPOLIS, Sept. 27, 1996-- Eli Lilly and Company announced today that it has received approval through the European Medicine Evaluation Agency (EMEA) in Europe to market Zyprexa(TM) in 15 European Union member countries for the treatment of schizophrenia, the long-term maintenance treatment of schizophrenia and the treatment of co-morbid depression, or depression that may occur with schizophrenia. Schizophrenia is one of the most chronic and debilitating of the mental illnesses, affecting 1 percent of the world's population. Schizophrenia is marked by the presence of positive symptoms, such as delusions and hallucinations, and negative symptoms, such as diminished emotions and low motivation. Many currently available older antipsychotic medications are perceived as having little or no effect on negative symptoms. These medications also have been linked to extrapyramidal syndrome (EPS) events, including abnormal muscle spasms, Parkinson's disease-like symptoms, abnormal jerking or writhing, and an inability to sit still. The Committee for Proprietary Medicinal Products (CPMP) cleared Zyprexa for marketing after evaluating the results of Lilly's data from more than 3,100 individuals in 22 countries, with more than 200 clinical investigators conducting the studies. Zyprexa is currently under review by the U.S. Food and Drug Administration and has not been approved for marketing anywhere outside Europe. Eli Lilly and Company is a global, research-based pharmaceutical corporation headquartered in Indianapolis, Ind., that is dedicated to creating and delivering superior health care solutions -- by combining pharmaceutical innovation, existing pharmaceutical technology, disease prevention and management and information technologies -- in order to provide customers worldwide with optimal clinical and economic outcomes. E-mail this page to a friend or colleague! To print, use this version