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Vitravene Available In U.S. For CMV Retinitis In AIDS Patients ATLANTA, GA and NEW ORLEANS, LA -- Nov. 9, 1998 -- CIBA Vision Corp. has launched Vitravene (fomivirsen sodium intravitreal injectable) for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS in the United States. The announcement was made at the American Academy of Ophthalmology annual meeting in New Orleans. Vitravene is the first in a class of novel therapeutics based on an antisense mechanism to be approved for marketing in the U.S. Vitravene is indicated for the local treatment of CMV retinitis in patients with AIDS who are intolerant of or have a contraindication to other treatments for CMV retinitis or who were insufficiently responsive to previous treatments for CMV retinitis. A marketing authorization application (MAA) submitted by CIBA Vision is currently under review with the European Agency for the Evaluation of Medicinal Products (EMEA) for the marketing of Vitravene in Europe. The recommended dose of Vitravene is 330 (micrograms). Treatment with Vitravene involves an induction and a maintenance phase. The induction dose for Vitravene should be one injection every other week for two doses. Subsequent maintenance doses should be administered once every four weeks after induction. Vitravene will be marketed directly to physicians and clinics. E-mail this page to a friend or colleague! To print, use this version