No Link Between MMR Vaccine, Inflammatory Bowel Disease And Autism
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No Link Between MMR Vaccine, Inflammatory Bowel Disease And Autism

LONDON, ENGLAND -- May 1, 1998 -- Researchers in Finland report in a research letter in this week’s issue of The Lancet that there is no link between the measles, mumps and rubella (MMR) vaccine and a new syndrome of chronic inflammatory bowel disease and autism.

The study, by professor Heikki Peltola, from the Helsinki University Central Hospital, Hospital for Children and Adolescents, Helsinki, Finland, and colleagues was performed in response to a Feb. 28, 1998 study published in The Lancet which suggested there may be a link between the vaccine and the conditions.

In the first report, penned by Dr. Andrew Wakefield and colleagues from the Royal Free Hospital, concluded that further investigations were needed to examine the syndrome and its possible relation to the MMR vaccine.

The Finnish researchers traced children who had received the MMR vaccine between 1982 and 1996. By the end of 1996, around three million MMR vaccine doses had been given in Finland.

In all, 31 children developed gastrointestinal symptoms (such as diarrhoea and vomiting) within 15 days of vaccination but the symptoms generally disappeared within a week. A one-year-old boy had diarrhoea for six weeks but he recovered and was healthy when checked almost six years later. No child developed autism or any similar syndrome.

"Over a decade's effort to detect all severe adverse events associated with MMR vaccine could find no data supporting the hypothesis that it would cause pervasive developmental disorder or inflammatory bowel disease," the researchers write.

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