Uterine Artery Embolization Effective and Safer Than Surgery for Uterine Fibroids: Presented at SIR
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Uterine Artery Embolization Effective and Safer Than Surgery for Uterine Fibroids: Presented at SIR

TORONTO, CANADA -- April 4, 2006 -- Uterine artery embolization (UAE) is a much safer procedure than surgery for treatment of symptomatic uterine fibroids, according to a study presented here at the 31st Annual Scientific Meeting of the Society of Interventional Radiology (SIR).

About 10% to 20% of women with fibroids require treatment that includes medical management, surgery or UAE, said presenter Sanjoy Kundu, MD, interventional radiologist, Scarborough General Hospital, and medical director, The Vein Institute of Toronto, Toronto, Canada.

In his study, Dr. Kundu and colleagues conducted a retrospective comparison of outcomes in women who presented with uterine fibroids between January 2003 and December 2004 -- 312 were treated by surgery and 65 by UAE. The surgical patients received a total abdominal hysterectomy (TAH, n = 194), myomectomy (n = 47), vaginal hysterectomy (n = 30) or a laparoscopic assisted vaginal hysterectomy (LAVH, n = 42).

Mean age was 42 years (30-51 in the surgery group and 30-52 in the UAE group. Both groups received pre-procedural antibiotics.

The average length of hospital stay for the surgical patients was 3.5 days (range 2-25 days) and for UAE patients it was 1.2 days (range 1-4). The rate of major complications in the surgical group was 6.3%, including 1 death. Other major complications included 2 bowel injuries, 4 urologic injuries, 8 cases of anemia requiring transfusion, and various other unspecified complications (n = 5). Rates of major complications by type of surgery were 7% with TAH, 2% with myomectomy, none with vaginal hysterectomy, and 14% with LAVH.

There were no major complications in the UAE group, Dr. Kundu said.

The surgical group had 3 cases of pulmonary embolism, 27 cases of infection. None of the UAE patients had either of these complications.

Post-operative emergency room treatment was required by 62 women in the surgery group, and 31 of them were admitted to hospital. In the UAE group, 5 patients required treatment in the ER and 3 were admitted.

Dr. Kundu summarized the findings of this study by stating that UAE is a safe and efficacious procedure with shorter length of hospital stay and fewer complications than major surgery. The morbidity rate was higher for vaginal hysterectomy and LAVH procedures than with TAH, he said.

[Presentation title: Comparison of Surgical Periprocedure Morbidity/Mortality & Length of Stay with UAE for Symptomatic Uterine Fibroids. Abstract 146]

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