Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

Pneumococcal Protein-D Conjugate Vaccine Safe to Coadminister With Other Routine Vaccinations: Presented at ESPID By Jenny Powers NICE, France -- May 12, 2010 -- Antibody responses elicited by pneumococcal nontypeable Haemophilus influenzae protein-D conjugate vaccine (PHiD-CV) coadministered with the diphtheria, tetanus, pertussis (DTaP), hepatitis B virus (HBV), poliomyelitis (IPV), and H influenzae type b (Hib) vaccine (DTaP-HBV-IPV-HiB) or DTaP-IPV-HiB were comparable for all vaccine pneumococcal serotypes except 18C, researchers reported here at the 28th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID). Menno R. van den Bergh, MD, Department of Paediatric Immunology and Infectious Disease, University Medical Center, Utrecht, and the Department of Paediatrics of the Spaarne Hospital, Hoofddorp, Netherlands, presented the results here on May 7. . The primary objective of his single-centre, single-blind study was to demonstrate noninferiority of PHiD-CV when coadministered with DTaP-IPV-Hib (group 2) as compared with the DTaP-HBV-IPV-HiB vaccine (group 1) at 1 month after the third dose in 520 healthy infants. Vaccines were given when the infants were aged 2, 3, and 4 months. Noninferiority of group 2 versus group 1 was demonstrated for protein D against all vaccine pneumococcal serotypes except 18C. For each vaccine pneumococcal serotype including 18C, percentages of infants reaching enzyme-linked immunosorbent assay (ELISA) 0.2 mcg/mL were in the same ranges for both PHiD-CV groups. For each vaccine group pneumococcal serotype including 18C, the percentages of infants reaching 33F-ELISA 0.2 mcg/mL and percentages reaching an opsonophagocytic activity titre of 8 were in the same ranges for both treatment groups. The lower antibody geometric mean concentrations for serotype 18C could be related to observed differences in anti-tetanus response, which were higher in group 1. Funding for this study was provided by GlaxoSmithKline. [Presentation title: Immunogenicity of PHiD-CV 3-Dose Primary Vaccination Co-Administered With Pediacel or Infanrix Hexa in the Netherlands. Abstract 24] E-mail this page to a friend or colleague! To print, use this version