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Pregnancy Success Rates High After UFE in Portuguese Study: Presented at SIR By Thomas R. Collins TAMPA, Fla -- March 15, 2010 -- Uterine fibroid embolisation (UFE) may be a first-choice treatment for women who want to become pregnant, contrary to previous findings that favoured myomectomy for women interested in becoming pregnant but who have benign tumours of the uterus, according to researchers here at the Society of Interventional Radiology (SIR) 35th Annual Scientific Meeting. The complication rates of the pregnancies in the study were surprisingly similar to the rates of the general population, said Joao Martins Pisco, MD, St. Louis Hospital, Lisbon, Portugal. “UFE is not a contraindication for patients who want to conceive,” Dr. Pisco said on March 14. “UFE may be the single effective treatment in some patients with uterine fibroids.” The study included 743 women who underwent UFE procedures, mainly after failure of a myomectomy or because hysterectomy was suggested as the only other option. The fertility rate of the women was 58.1%, which is comparable to the rates for those who undergo myomectomy the -- gold standard for symptomatic fibroids in women who want to get pregnant, Dr. Pisco said. UFE has advantages over myomectomy in certain cases. Women with multiple or large fibroids could face difficulties with myomectomy because it might involve removal of too much of the uterus. UFE can avoid this problem because it involves merely releasing tiny particles into the blood vessels that feed the tumours. Of the 743 women in the study, 74 wanted to become pregnant but had been unable to do so. Subsequently 43 of the women (58%) became pregnant. Their average age was 35 years. The time between the UFE and conception ranged from 2 to 22 months. The study reported 36 completed pregnancies -- 30 successful live births, 5 abortions (1 induced and 4 spontaneous), and 1 stillbirth. Seven of the pregnancies are ongoing. The percentages of spontaneous abortions (11.1%), preterm delivery (10.0%), and low-birthweight babies (13.3%) were similar to the general population. Asked whether the favourable results might have been due to a different technique that was taken because the interventional radiologists were mindful that the woman wanted to become pregnant, Dr. Pisco said that extra caution was, in fact, taken. “Always I ask them if they want to get pregnant or not,” Dr. Pisco said. “If they want to get pregnant, my embolisation technique is different. I try to embolise only the small vessels.” [Presentation title: The Outcome of Pregnancy Following Uterine Fibroid Embolization. Abstract 50] E-mail this page to a friend or colleague! To print, use this version