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Sleep Interventions Improve Quality of Life in Older Patients With Alzheimer’s Disease, Dementia: Presented at ADI By Jenny Powers THESSALONIKI, Greece -- March 15, 2010 -- Interventions to improve the sleep cycles of patients with Alzheimer’s disease (AD) and dementia have beneficial effects on the distress experienced by all patients and improved sleep cycles in some patients, according to a study reported here at the 25th Conference of Alzheimer’s Disease International (ADI). Yamamoto Matsuzawa, Nursing College in Komagane, Komagane, Japan, reported the results here on March 12 on behalf of her colleagues. This study’s goal was to assess the effects of an intervention to improve sleep-activity cycles of older persons with AD. For the study, 65 patients from long-term care facilities were enrolled and 40 patients’ data were analysed. The sleep-activity cycle of patients was recorded over 48 hours and residents’ medications were examined from medical charts. Sleep-activity cycles were evaluated by a caregiver in the long-term care facilities; behaviour before and after intervention was evaluated using the Multidimensional Observation Scale for Elderly Subjects (MOSES). In all, 70% of the patients were diagnosed with dementia that included Alzheimer’s dementia, cerebrovascular dementia, and senile dementia; 80% of the patients had sleep-activity cycle disorders (40% had hyperactive disorder, 32.5% hypoactive disorder, and 7.5% circadian rhythm disorder). The mean number of medications per resident was 2.9 which included 15%, 55%, 32.5%, and 22.5% of patients taking benzodiazepines, antihypertensives, purgative, and antidementia medications, respectively. No prescribed medication was taken by 12.5% of the patients. Intervention regardless of type had benefit; the MOSES psychological distress score decreased in all residents who received the intervention, as compared with untreated patients. Also, the sleep-activity cycle of 2 residents was improved. From these results it was concluded that interventions to improve sleep in older persons with dementia have benefit in decreasing distress and, in some cases, improve sleep cycles. [Presentation title: An Intervention to Improve Sleep-Activity Cycles of Older Persons With Dementia. Abstract P044] E-mail this page to a friend or colleague! To print, use this version