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New Alzheimer’s Test Offers Better Opportunities for Early Detection KNOXVILLE, Tenn -- March 11, 2010 -- Early detection is key to more effective treatment for Alzheimer’s disease and other forms of cognitive impairment, and new research shows that a test developed is more than 95% effective in detecting cognitive abnormalities associated with these diseases. The test, called CST -- for computerized self test -- was designed to be both effective and relatively simple for medical professionals to administer and for patients to take. The research is published early online and will appear in the April issue of the Journal of Alzheimer’s Disease. Rex Cannon, University of Tennessee, Knoxville, Tennessee, worked with a team of researchers to develop CST. The impetus for the test came from data showing that 60% of Alzheimer’s cases are not diagnosed in the primary care setting, and that those delays lead to missed treatment opportunities. “Early detection is at the forefront of the clinical effort in Alzheimer’s research, and application of instruments like CST in the primary care setting is of extreme importance,” said Cannon. The CST is a brief, interactive online test that works to asses various impairments in functional cognitive domains -- in essence, it’s a “fitness test” of sorts for the basic functions of thinking and processing information that are affected by Alzheimer’s and milder forms of cognitive impairment. The study showed that the CST was substantially more effective and more accurate in detecting the presence of Alzheimer’s and other forms of cognitive impairment in patients than other existing tests. The CST had a 96% accuracy rate compared with a 71% and 69% for the tests that are currently in use. Part of the goal in developing the test, according to Cannon, was to ensure that the test is useful in the primary care setting, where physicians may not have detailed training in recognising cognitive impairments, but where an early diagnosis may do the most good for patients. “Computerised testing is a developing and exciting area for research,” said Cannon, who noted that the test can provide an objective way to determine what diseases may affect the patient and provide information to begin treatments that can blunt the effects of Alzheimer’s. SOURCE: University of Tennessee at Knoxville E-mail this page to a friend or colleague! To print, use this version