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Nicotine Replacement Therapy Helps Reduce Withdrawal Symptoms in Hospitalised Patients: Presented at SRNT By Liz Meszaros BALTIMORE, Md -- February 26, 2010 -- Nicotine replacement therapy (NRT) can alleviate nicotine withdrawal symptoms in smokers who have been hospitalised with heart disease, according to a study presented here at the 2010 Society for Research on Nicotine and Tobacco (SRNT) Annual Meeting. “NRT can help hospitalised smokers reduce their craving to smoke, and thus increase their comfort during their hospital stay, and improve the likelihood of achieving long-term success,” said lead author Kerri Mullen, University of Ottawa Heart Institute, Ottawa, Ontario. “The use of other pharmacotherapies to treat withdrawal symptoms in patients hospitalised with heart disease warrants investigation,” noted Dr. Mullen here on February 25. For the study, Dr. Mullen and colleagues reviewed the charts from a consecutive series of 106 smokers with a mean age of 54.2 years who had been admitted to a tertiary-care cardiac facility and had been referred to an in-hospital smoking-cessation program. These patients had smoked for a mean of 34.3 years, and 74% of them were male. In all, 65.1% of patients received NRT, while the remaining 34.9% did not (noNRT). Age, number of years of smoking, and feelings of conviction/confidence in smoking cessation did not differ significantly between the NRT and noNRT groups. Nicotine withdrawal symptoms were measured using the Minnesota Nicotine Withdrawal Scale at baseline and at 24 to 48 hours following baseline. Mean nicotine withdrawal symptom scores decreased by 1.51 in the NRT group, and by .21 in the noNRT group. Mixed model repeated measures analysis showed a significant main effect both for time (P = .008) and for NRT treatment (P = .021). [Presentation title: Severity of Nicotine Withdrawal Symptoms and Effect of Nicotine Replacement Therapy in Smokers Hospitalized With Heart Disease. Abstract POS2-73] E-mail this page to a friend or colleague! To print, use this version