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Overall Incidence of Major Bleeding After Image-Guided Biopsies Low RESTON, Va -- February 19, 2010 -- Even among patients who have taken aspirin in proximity to an image-guided percutaneous biopsy, risk of major bleeding associated with the procedure is low, according to a study published in the March issue of the American Journal of Roentgenology. “With the evolution of imaging guidance, percutaneous biopsy has become a valuable tool in obtaining tissue for diagnosis,” said lead author Thomas D. Atwell, MD, Department of Radiology, Mayo Clinic, Rochester, Minnesota. “Unfortunately, this procedure is not without risk, and haemorrhage is the most feared complication after biopsy.” The study included a retrospective review of percutaneous biopsies performed at the Mayo Clinic in Rochester over the course of 6 years. “Among the 15,181 percutaneous biopsies performed during the study period, only 70 haemorrhages (0.5%) were identified within 3 months of biopsy,” said Dr. Atwell. “The incidence of bleeding in patients taking aspirin within 10 days before biopsy was 0.6% (18/3,195).” “Our study shows that the overall incidence of major bleeding after imaging-guided percutaneous needle biopsy is low, and recent aspirin therapy does not appear to significantly increase the risk of such bleeding complications,” said Dr. Atwell. “Significant bleeding after percutaneous biopsy is exceptionally rare,” he said. “In most cases, percutaneous biopsy can be performed in patients with recent aspirin use. In those patients undergoing elective, non-urgent deep organ biopsy, scheduling the biopsy 10 days after the last dose of aspirin is a reasonable, but not a necessary, precaution.” SOURCE: American Roentgen Ray Society E-mail this page to a friend or colleague! To print, use this version