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SIR: Peripheral Cutting Balloon Comparable to Angioplasty for Dialysis-related Stenosis By M. M. Pennell PHOENIX, AZ -- March 31, 2004 -- Use of a peripheral cutting balloon (PCB) may be as effective as standard angioplasty for treatment of haemodialysis-related stenosis, according to results of a 340-patient comparative study presented here March 29th at the Society of Interventional Radiology 29th Annual Meeting. The 6-month results suggest that PCB may be slightly better than standard angioplasty, but the trend did not reach statistical significance, said Thomas M. Vesely, MD, Mallinckrodt Institute of Radiology, St. Louis, Missouri, United States. One hundred and seventy-three patients were randomised to PCB: 101 patients with narrowed but patent grafts and 72 with thrombosed grafts. Ninety-four of the 167 patients randomised to angioplasty had stenotic grafts while 73 had thrombosed grafts. The primary endpoint was target-lesion primary patency at 6 months. Forty-eight percent of the PCB group and 41% of the angioplasty group reached this endpoint (P = .373), said Dr. Vesely. The procedural success rate for PCB was 81%, while success in the angioplasty group was 75% (P = .24). In both arms, patency rates declined and at 6 months; the primary patency in the access circuit for patients with stenotic grafts was 47% in the PCB arm and 41% in the angioplasty arm, which was not statistically significant. In patients with thrombosed grafts, PCB use was associated with a primary patency rate of 37.5% versus 29% in the angioplasty arm. Again, while the difference was greater, it did not reach statistical significance. There were 8 device-related complications in the PCB group: 5 venous ruptures/perforations and 3 venous dissections. Seven of the complications were successfully treated with angioplasty or stenting. There were no procedural complications in the angioplasty arm. [Study Title: Use of Peripheral cutting balloon to treat haemodialysis-related stenoses. Abstract 514] E-mail this page to a friend or colleague! To print, use this version