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| |  Ambulatory BP Monitoring Can Disturb Sleep and Affect Results WASHINGTON, DC -- December 17, 2009 -- A widely used test for measuring nighttime blood pressure (BP) may interfere with patients’ sleep, thus affecting the results of the test, according to a study published early online and appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology. “Blood pressure measured during sleep correlates better with heart attacks and strokes compared with blood pressure measured in the doctor’s office,” said Rajiv Agarwal, MD, Indiana University and Veterans Affairs Medical Center, Indianapolis, Indiana. “However, if blood pressure measurement disturbs sleep, then it may weaken the relationship between ‘sleeping BP’ and these cardiovascular events.” Dr. Agarwal and Robert Light, of Indiana University, analysed the results of 24-hour blood pressure monitoring in 103 patients with kidney disease. As part of a research study, the patients’ activity levels were measured using an actiwatch. “We were measuring activity, sleep, and ambulatory BP for diagnosing masked hypertension and found this interesting observation,” explained Dr. Agarwal. The lack of the normal nighttime ‘dip’ in blood pressure was related to increased activity levels, because the blood pressure monitor was disturbing the patients’ sleep. On nights when patients were using the blood pressure monitor, they spent an average of 90 minutes less time in bed. They also spent less time asleep and slept less efficiently. Patients who awoke at night during blood pressure monitoring were 10 times less as likely to have the normal nighttime ‘dip.’ “Nighttime blood pressure is lower not because of the time of the day, but because people are asleep,” said Agarwal. “The ambulatory monitoring technique can disturb sleep, and therefore raise the nighttime blood pressure as an artifact.” “Thus sleep quality should be taken into account when interpreting blood pressure during sleep,” added Dr. Agarwal. He noted that the wristwatch actigraph provides a simple and useful way of measuring activity during 24-hour blood pressure monitoring. This Veterans Administration study was limited to older veterans with kidney disease. “Whether similar results will be obtained in younger people remains to be seen,” he said.
SOURCE: American Society of Nephrology
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