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Pregnancy Does Not Worsen Outcomes Among Women With Breast Cancer: Presented at SABCS By Ed Susman SAN ANTONIO, Tex -- December 11, 2009 -- Researchers suggested here at the 32nd Annual San Antonio Breast Cancer Symposium (SABCS) that young women with breast cancer who become pregnant might be able to take their babies to term without compromising favourable outcomes. Researchers from Spain followed outcomes among 121 women aged 35 years or younger when breast cancer was diagnosed, and followed their outcomes over a period that, for some patients, exceeded 6 years. The average follow-up was 4 years. “What [we] found was that women who became pregnant after their diagnosis and treatment for breast cancer did not have outcomes that were any worse than [that of] women the same age who did not become pregnant,” said Octavi Cordoba Cardona, MD, Hospital Universitari Vall d’Hebron, Barcelona, Spain, during a poster presentation here today. “I really don’t have any explanation for this.” Of the women who were followed, 20 became pregnant. He said 8 women interrupted the pregnancy because they were taking tamoxifen. The other 12 women allowed their pregnancy to continue, and all had full-term, normal-birth babies. No miscarriages were observed. “A significant proportion of patients diagnosed with breast cancer at young age get pregnant,” said Dr. Cordoba. After 5 years, 95% of the women who became pregnant achieved disease-free survival compared with 62% of the women who did not get pregnant (P < .01). In addition, 100% of the women who became pregnant survived for at least 5 years, compared with 835 of the women who did not become pregnant (P < .01). The median age at diagnosis was 31 years in the entire cohort, and 83.2% of the women who did not get pregnant and 81% of the women who did get pregnant were diagnosed with invasive ductal carcinoma. About 51% of the nonpregnant women and 44% of the pregnant women had positive axillary nodes. About 89% of the women who did not get pregnant were treated with adjuvant chemotherapy compared with 80% of the women who did get pregnant. About 685 of women who did not get pregnant underwent hormonal therapy compared with 35% of those who did get pregnant (P = .01). [Presentation title: Pregnancy After Breast Cancer in Young Patients Does Not Worsen the Outcome of Breast Cancer. Abstract 2062] E-mail this page to a friend or colleague! To print, use this version