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Antithrombotic Medication Use Not Improving Among Ischaemic Stroke Survivors LOS ANGELES -- December 4, 2009 -- Approximately 20% of ischaemic stroke survivors are not taking their antithrombotic medications, according to a study originally designed to determine whether the use of these medications increased among stroke survivors over a 7-year period. The study also found that individuals who were younger, female, or Hispanic were less likely to be taking antithrombotic agents. The findings appear in the January 2010 issue of the American Journal of Preventive Medicine. “Prior studies have shown that nearly all stroke survivors receive such medications in the hospital,” said lead author Eric M. Cheng, MD, David Geffen School of Medicine at UCLA and the Veterans Administration Greater Los Angeles Healthcare System, both in Los Angeles, California. ”However, it was not known whether stroke survivors continued to take this type of medication after they were discharged from the hospital.” Researchers analysed data compiled from the annual Medical Expenditure Panel Survey (MEPS) from 2000 to 2006. In the 7 annual MEPS data sets, 4,168 people reported having had a stroke. The study authors looked at the use of antithrombotic agents, which include aspirin, other antiplatelet medications, and anticoagulants. Pooling results across the 7 years, the researchers found that 75% of the stroke survivors were using an antithrombotic agent, with 66% reporting taking an antiplatelet medication and 57% taking aspirin. After excluding those individuals who reported not taking aspirin because it was unsafe for them, the researchers calculated that 81% were using antithrombotic agents. The study authors also found that men, older individuals and non-Hispanic individuals were more likely to be taking antithrombotic agents. Overall, the authors concluded that while the level of use of antithrombotic agents appeared high, further research should investigate whether the remaining 20% of stroke survivors had indications for antithrombotic therapy that outweighed any contraindications, and, if so, why they were not taking these medications, particularly younger, female and Hispanic patients. SOURCE: University of California, Los Angeles E-mail this page to a friend or colleague! To print, use this version