Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

Recommendations on Nonanaesthesiologist Administration of Propofol for GI Endoscopy Safe; Proper Training and Patient Selection Are Crucial OAK BROOK, Ill -- December 3, 2009 -- The worldwide safety experience of endoscopist-administered propofol sedation now exceeds 600,000 patients. The low rate of serious adverse events underscores the safety of nonanaesthesiologist-administered propofol (NAAP) for gastrointestinal (GI) procedures, provided that it is administered by a team of individuals who have received training specific to the administration of propofol according to the “Position statement: nonanaesthesiologist administration of propofol for GI endoscopy” issued by the 4 major gastroenterology and hepatology societies. “Based on the evidence, the administration by nonanaesthesiologists of propofol versus sedation with commonly used agents is comparable with respect to their efficacy and safety profiles. Gastroenterologists and registered nurses in many countries have successfully acquired the skills necessary to safely administer propofol-based sedation. Proper training and patient selection are crucial for the safe practice of nonanaesthesiologist-administered propofol sedation,” said Lawrence B. Cohen, MD, chair of the Sedation Task Force. “Although there are no cost-effectiveness data comparing NAAP to anaesthesiologist-administered propofol sedation for GI endoscopy, it is known that the use of anaesthesiologist-administered sedation for healthy, low-risk patients undergoing routine GI endoscopy results in higher costs with no proven benefit with respect to patient safety or procedural efficacy.” The statement is issued jointly by the American Association for the Study of Liver Diseases (AASLD), the American College of Gastroenterology (ACG), the American Gastroenterological Association (AGA) Institute, and the American Society for Gastrointestinal Endoscopy (ASGE). A 4-member committee composed of a representative from each society was convened to develop a document designed to provide an evidence-based assessment of propofol-mediated sedation by properly trained gastroenterologists and other nonanaesthesiologists. The document was reviewed and approved by the governing boards of all 4 societies and is being published in the December issues of Hepatology, the American Journal of Gastroenterology, Gastroenterology, and GIE: Gastrointestinal Endoscopy. A number of recommendations are made in the statement regarding NAAP for GI endoscopy: Safety of NAAP equivalent to “standard” sedation: The safety profile of NAAP is equivalent to that of “standard” sedation with commonly used agents such as a narcotic and a benzodiazepine with respect to the risks of hypoxaemia, hypotension, and bradycardia for upper endoscopy and colonoscopy. The safety profile of NAAP when it is administered during endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) appears to be equivalent to that of standard sedation. The worldwide experience with NAAP during these procedures (EUS and ERCP), however, is insufficient to draw definitive conclusions about its use in these settings. Efficacy of NAAP for GI endoscopy: For upper endoscopy, colonoscopy, ERCP, and EUS, the time for sedation induction is shorter with NAAP than with sedation with commonly used agents. Recovery time for upper endoscopy, colonoscopy, ERCP, and EUS when using NAAP is shorter than for sedation with a narcotic and a benzodiazepine. Patient satisfaction with NAAP is equivalent or slightly superior to that with standard sedation. Economics of NAAP for GI endoscopy: For ERCP and EUS, NAAP is more cost-effective than standard sedation. Nonanaesthesiologist-administered propofol sedation improves practice efficiency when compared to sedation with commonly used agents. The use of anaesthesiologist-administered sedation for healthy, low-risk patients undergoing routine GI endoscopy results in higher costs with no proven benefit with respect to patient safety or procedural efficacy. Training guidelines for NAAP for GI endoscopy: · NAAP requires the acquisition of skills and abilities that are distinct and apart from those necessary for standard sedation. Training programs should provide both didactic and practical, hands-on learning experiences. · Individuals administering propofol should be proficient in the management of upper and lower airway complications, including manual techniques for re-establishing airway patency, use of oral and nasal airway devices, and proper bag-mask ventilation. Basic life support or advanced cardiac life support certification is required. Training with life-size manikins and/or human simulators improves the acquisition of these skills. · Preceptorship is an important element of training for physicians and nursing personnel acquiring the skills to administer propofol. · Capnography reduces the occurrence of apnoea and hypoxaemia during ERCP/EUS and upper endoscopy/colonoscopy. SOURCE: American Society for Gastrointestinal Endoscopy E-mail this page to a friend or colleague! To print, use this version