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Exercise Alone Can Improve Insulin Sensitivity in Obese Sedentary Adolescents CHEVY CHASE, Md -- September 4, 2009 -- A moderate aerobic exercise program, without weight loss, can improve insulin sensitivity in both lean and obese sedentary adolescents, according to a study that will be published in an upcoming issue of the Journal of Clinical Endocrinology & Metabolism. "Because weight loss can be difficult to achieve and maintain in obese sedentary children, the purpose of this study was to determine whether a controlled exercise program, without any diet intervention and with no intention of weight loss, would improve fat distribution and sensitivity to insulin," senior author Agneta Sunehag, MD, Baylor College of Medicine, Houston, Texas. "We found that a 12-week moderate aerobic exercise program consisting of four 30-minute workouts a week increased fitness and improved insulin sensitivity in both lean and obese adolescents." In this study, 29 adolescents (14 lean and 15 obese) completed the 12-week moderate aerobic exercise program. During the exercise sessions, individuals worked out on a treadmill, elliptical or bicycle. The goal of each exercise session was to get the participants' heart rate to increase to at least 70% of their maximum capacity. Glucose and insulin concentrations were measured both before and after the exercise program. Cardiovascular fitness was determined using an oxygen consumption test which consists of measuring oxygen uptake of the participant during a treadmill exercise where speed and incline is increased every 3 minutes until they reached their maximum exercise capacity. "Many studies include both diet and exercise interventions, which makes it difficult to determine which intervention is most effective and best accepted by adolescents," said Dr. Sunehag. "Our findings show that exercise alone can increase fitness and improve insulin sensitivity, making an aerobic program like the one used in this study a potential useful tool in preventing obesity-related illnesses." SOURCE: The Endocrine Society E-mail this page to a friend or colleague! To print, use this version