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Home Haemodialysis, Deceased Donor Kidney Transplant Have Comparable Survival Rates TORONTO -- August 20, 2009 -- Patients who receive night home haemodialysis live just as long as those who receive kidney transplants from deceased donors, according to a study published in the September issue of Nephrology Dialysis Transplantation. For the study, 1,239 patients were followed for up to 12 years. Night home haemodialysis patients were compared with patients who received either a deceased donor kidney transplant or a living donor kidney transplant. The study found that the survival between night home dialysis patients and those who received kidney transplants from deceased donors was comparable, while the survival of the patients who received a transplant from a living kidney donor was better than both the other groups. The results suggest that night home haemodialysis may be a “bridge to transplant” or a suitable alternative to transplant should a patient be too high risk for a transplant or not be able to get a living or deceased donor as the organ shortage continues. “This study allows me to actually answer what my patients have been asking me for over a decade: ‘What does night home haemodialysis mean for my life span?’ I can now tell them that this specific dialysis option is as good as getting a transplant from a deceased donor,” said Dr. Christopher Chan, MD, Home Hemodialysis at Toronto General Hospital, University Health Network, and University of Toronto, Toronto, Ontario. Until now, there has been no long-term data on night home haemodialysis patient survival, or on how this type of treatment compares with transplantation. In the study, data of patients receiving night home haemodialysis was carefully matched with deceased and living donor kidney transplantation mortality data from the US Renal Data System on characteristics such as age, race, diabetic status, and duration of treatment with conventional in-centre dialysis prior to treatment. The proportion of deaths in each group was then measured, with final figures of 14.7% for night home haemodialysis patients; 14.3% for patients with transplants from deceased donors; and 8.5% for patients with transplants from living donors. These results diverge from the evidence to date that dialysis is inferior to transplantation, pointed out Dr. Chan, adding that there is much benefit to be gained by long, frequent dialysis. SOURCE: University Health Network E-mail this page to a friend or colleague! To print, use this version