Implantable Lenses Shows Promise for as Treatment for High Myopia
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Implantable Lenses Shows Promise for as Treatment for High Myopia

CHICAGO -- July 13, 2009 -- Implantable lenses made of a collagen-like substance appear to provide stable correction of moderate to high myopia over 4 years of follow-up, according to a study published in the July issue of Archives of Ophthalmology.

"Laser-assisted in-situ keratomileusis (LASIK)has gained widespread popularity as a safe and effective surgical method for the correction of myopia, but patients with high myopia or thin corneas face some restrictions in avoiding the risk of developing keratectasia," the authors wrote as background information in the article.

An implantable lens consisting of a biocompatible collagen copolymer was developed to overcome these disadvantages, and has been reportedly effective in correcting moderate to severe vision problems. The implantation procedure is largely reversible and the lens is interchangeable, unlike LASIK. However, complications such as the formation of cataracts, loss of cells lining the eye and glaucoma have been reported and are expected to increase with time.

To assess the long-term clinical outcomes of the lens implantation, Kazutaka Kamiya, MD, University of Kitasato School of Medicine, Kanagawa, Japan, and colleagues evaluated 56 eyes of 34 patients who underwent implantation of the collagen copolymer lens. Routine post-operative examinations were conducted 1, 3, and 6 months and 1, 2, and 4 years later.

At 4 years after surgery, 44 of the eyes (79%) were within 0.5 diopter of the targeted correction and 52 (93%) were within 1 diopter.

The authors suggest that collagen polymer lens implantation "results were good in all measures of safety, efficacy, predictability and stability for the correction of high myopia throughout the 4-year follow-up," they wrote. "To our knowledge, this is the longest study to assess the refractive outcomes and adverse events" of the collagen copolymer lens implantation for myopia.

"In addition, no vision-threatening complications occurred throughout the follow-up period," they concluded. The authors note that their findings suggest that collagen copolymer lens implantation "may be a good alternative for the treatment of moderate to high myopia. More prolonged careful observation for longer than 4 years is necessary to assess late-onset complications of this surgical technique."

SOURCE: Archives of Ophthalmology

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