Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

FDG-PET Can Help Prevent Unnecessary Surgery in Patients With Colorectal Liver Metastases: Presented at ESMO-GI By Jenny Powers BARCELONA, Spain -- July 1, 2009 -- Selection of patients who will benefit from surgical treatment of colorectal liver metastases is significantly improved by adding 2-(18F) fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) to the presurgical disease staging, according to research presented here at the 11th World Gastrointestinal Cancer Congress of the European Society for Medical Oncology (ESMO-GI). Theo J. Ruers MD, Department of Surgery, The Netherlands Cancer Institute, Amsterdam, the Netherlands, indicated that the staging of disease is crucial to avoid futile laparotomy wherein the tumour is either beyond surgical treatment or benign. Dr. Ruers presented his findings in a presentation on June 25. To determine patients who will benefit from surgical treatment of colorectal liver metastases, Dr. Ruers and colleagues added staging by PET with FDG to the presurgical work-up. The primary endpoint of the randomised study was reduction of the number of futile laparotomies, defined as any laparotomy that did not result in complete tumour treatment, that revealed benign disease, or that did not result in a disease-free survival period longer than 6 months. A total of 150 patients with colorectal liver metastases who had been selected for surgical treatment by imaging with computed tomography (CT) scan were randomly assigned to CT imaging only (n = 75) or CT imaging plus FDG-PET (n = 75). The baseline characteristics of the patients were similar for both treatment arms. The CT scan only group had 34 (45%) futile laparotomies whereas this number was reduced to 21 (28%) in the group with FDG-PET added and the relative risk reduction was 38% (95% confidence interval, 4%-60%). Dr. Ruers concluded that incorporating FDG-PET to the work-up for surgical resection of colorectal liver metastases greatly improved the selection of patients who will benefit from surgery and prevents unnecessary surgery in 1 out of 6 patients. [Presentation title: Improved Selection of Patients for Hepatic Surgery of Colorectal Liver Metastases With FDG-PET: A Randomized Multicentre Study. Abstract PD-0014] E-mail this page to a friend or colleague! To print, use this version