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Cataract Surgery More Frequent in Older Cornea-Transplant Patients: Presented at ARVO By Ed Susman FORT LAUDERDALE, Fla -- May 7, 2009 -- About 40% of patients over the age of 51 who received a cornea transplant required postsurgical cataract excision, but the need to perform postsurgical cataract excision among people younger than 51 years of age was relatively rare, researchers reported here at the Association for Research in Vision and Ophthalmology (ARVO) 2009 Annual Meeting. Researchers at the New York Medical College, Valhalla, New York, reviewed the charts of patients who underwent cornea transplants from December 1997 through January 2007. The research team identified 195 patients who underwent the procedure. "Only 13.3% of the eyes of the young to middle-aged patients [that required] penetrating keratoplasty … resulted in visually significant cataracts requiring extraction," said Tehara Bailey, medical student, New York Medical College, presenting the findings here in a poster presentation May 4. The research team, which also included Gerald Zaidman, MD, and Revathi Naadimuthu, MD, ophthalmologists, Westchester Medical Center at New York Medical College, performed a retrospective analysis of factors that predisposed patients undergoing corneal transplant to require later cataract extraction. The younger group in this study included 58 patients aged 25 to 35 years. The middle group included 82 patients aged 36 to 50 years. The older group included 55 patients aged 51 to 65 years. Overall, 26 patients required cataract extraction due to rejection, intraocular pressure, or the need for regrafting, but only 2 cataract extractions occurred among the younger patients, and only 3 in the middle age group. The team identified 21 patients in the older group that required cataract extraction. Overall, 17% of the subjects developed cataracts, but the cataracts were most problematic among the older group, Bailey reported. The most common postsurgical complication was keratoconus, seen in 82.8% of the younger group, 65.9% of the middle group, and 38.2% of the older patients. The team noted, however, that postoperative complications did not correlate to the need for cataract extraction. These results indicate that physicians who perform corneal transplants -- especially if the transplants occur in individuals over the age of 51 years -- should be counseling their patients about the possibility of having to perform a later cataract extraction. Among the older patients, the causes for cataract extraction included 3 cases of keratoconus, 9 cases of Fuch's dystrophy, 5 cases of herpes simplex keratitis, 2 cases of lattice dystrophy, and 2 other undefined causes. [Presentation title: The Incidence of Cataract Extraction Following Corneal Transplantation in Young and Middle-Aged Patients. Abstract 2207-D738] E-mail this page to a friend or colleague! To print, use this version