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Eye Surgery Fails to Alter Psychiatric Outcome in Children With Intermittent Exotropia: Presented at ARVO By Ed Susman FT. LAUDERDALE, Fla -- May 7, 2009 -- Children who exhibit intermittent exotropia often develop mental illness later in life, but researchers here at the Association for Research in Vision and Ophthalmology (ARVO) 2009 Annual Meeting say that correcting the problem surgically does not appear to alter the psychiatric outcome. "Strabismus surgery, regardless of success or age at surgery, for children with intermittent exotropia did not decrease or otherwise alter the development of mental illness by early adulthood," said Roman A. Barraza, Mayo Clinic, Rochester, Minnesota, at a presentation on May 5. The retrospective study included 183 patients (<19 years) diagnosed with intermittent exotropia from Olmsted County, Minnesota, between January 1975 and December 1994. Of these, 97 (53.3%) were later diagnosed with mental illness. Of the 183 patients in the study, the researchers identified 58 patients with intermittent exotropia who underwent surgery and compared outcomes with the 125 children in the study group that did not have surgery. Of the children who developed mental illness at a mean age of 23.3 years, 33 had surgery and 64 did not. The difference was not statistically significant (P = .75). Previous studies determined that children who exhibit intermittent exotropia are 3.1 times more likely to develop a mental illness than control subjects. The researchers in the current study found that the likelihood of developing mental illness was the same regardless of the age at which the children had surgery or whether the surgery was successful. Of the 86 patients who did not develop mental illness, strabismus surgery, when it occurred, was not more common (P = .71) or at a younger age (P = .15) when compared with the 97 patients who later developed mental illness. Funding for this study was provided by Research to Prevent Blindness. [Presentation title: Surgical Correction of Childhood Intermittent Exotropia Does Not Influence the Development of Mental Illness. Abstract 1992-D767] E-mail this page to a friend or colleague! To print, use this version