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Hepatitis B Injection Approved for Treating Acute Exposure NEW YORK -- April 23, 2009 -- Health Canada has approved the hepatitis B immune globulin (human) injection (HepaGam B) for treating acute exposure to hepatitis B virus (HBV). Specifically, the approval is for post-exposure prophylaxis (PEP) for acute exposure to blood containing hepatitis B surface antigen (HBsAg), perinatal exposure of infants born to HBsAg-positive mothers, sexual exposure to HBsAg-positive persons, and household exposure to persons with acute hepatitis B infection. The most common expected adverse drug reactions for intravenous immune globulins are chills, fever, headaches, vomiting, allergic reactions, nausea, arthralgia, and moderate low back pain. SOURCE: Cangene E-mail this page to a friend or colleague! To print, use this version