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Obesity Raises Risk of GERD BETHESDA, Md -- August 20, 2008 -- Several scientific studies in the August issue of the American Journal of Gastroenterology examine the association between obesity and the risk of gastro-oesophageal reflux disease (GERD). Frank K. Friedenberg, MD, Temple University School of Medicine, Philadelphia, Pennsylvania, and colleagues provide an extensive overview of scientific research on the epidemiologic and pathophysiologic associations between obesity and GERD. Several studies featured in the article highlight the correlation between increasing body mass index and the frequency and severity of acid reflux symptoms. One particular study found that accumulation of abdominal fat, as measured by the waist-to-hip ratio, may be the most important risk factor for the development of acid reflux and related complications such as Barrett's oesophagus and oesophageal adenocarcinoma. The authors also examined data on the effects of weight loss through diet or surgical methods on acid reflux disease. Several studies suggest weight loss through caloric restriction was beneficial in reducing GERD symptoms. When the authors compared the different surgical approaches for weight loss, Roux-en-Y gastric bypass appeared to be the best method and was most consistently associated with improvement in the symptoms and findings of GERD. "The mechanism of action through which this surgery is successful at improving GERD may be independent of weight loss and needs further examination," said Dr. Friedenberg. SOURCE: American College of Gastroenterology E-mail this page to a friend or colleague! To print, use this version