Good Long-Term Prognosis After West Nile Virus Infection
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Good Long-Term Prognosis After West Nile Virus Infection

PHILADELPHIA -- August 18, 2008 -- The long-term prognosis of patients infected with West Nile virus is good, according to a new study appearing in the August 19 issue of Annals of Internal Medicine. This is the largest study of the long-term outcomes of West Nile virus infection.

"This is the first study to comprehensively look at a large population of infected persons to study the long-term effects of West Nile virus," said study author Mark Loeb, MD, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario.

"We found that both physical and mental functions, as well as mood and fatigue, seemed to return to normal in about 1 year."

Researchers followed 156 patients between 2003 and 2007 to record patterns of physical and mental effects of West Nile virus infection. Researchers anticipated greater severity and a longer course of depression and fatigue in participants with neurological problems.

However, they found symptoms and recovery times to be similar to those in participants without neurological consequences of infection. Pre-existing health conditions were an important factor in long-term prognosis.

Patients who were healthy at the time of infection returned to normal health more quickly on average than those who had pre-existing conditions.

Researchers say the data might help patients infected with West Nile virus and their healthcare providers know the expected rate of recovery of physical and mental functioning, fatigue, and depression.

SOURCE: American College of Physicians

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