Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

Sucrose as Analgesic for Newborns Only Effective in Certain Procedures OTTAWA, Ontario -- July 1, 2008 -- Using sucrose to reduce pain in newborns undergoing painful procedures should be limited to babies having venipuncture for the newborn screening test but not for intramuscular injections, according to a study published in the July 1 issue of the Canadian Medical Association Journal. Anna Taddio, PhD, University of Toronto, Toronto, Ontario, and colleagues aimed to evaluate the effectiveness and safety of sucrose in newborns undergoing various medical procedures within 2 days of birth in this double-blind, randomised, controlled trial. Included in the study were 240 newborns of diabetic mothers (n = 120) and nondiabetic mothers (n = 120) born at Mount Sinai Hospital, Toronto, Ontario. Each newborn received 2 mL of a 24% sucrose solution or a placebo solution before all procedures. The Premature Infant Pain Profile was used to assess pain. Researchers found that the overall mean pain score was lower among newborns who received sucrose compared with those who received a placebo. During venipuncture, newborns who received sucrose had lower pain scores compared with those who received a placebo. However, they did not observe analgesic effects during intramuscular injections of vitamin K in either treatment group or during repeated heel-lancing for blood glucose monitoring in newborns of diabetic mothers. When each procedure was analysed separately, the authors found that the effectiveness of sucrose was limited to venipuncture for the newborn screening test. As all newborns experience pain from medical procedures in the first days of life, the results of this study will be helpful in reducing pain responses. The authors recommend updating pain management guidelines to reflect these findings. SOURCE: Canadian Medical Association Journal E-mail this page to a friend or colleague! To print, use this version