Micafungin Approved in Europe for Treatment and Prevention of Fungal Infections
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Micafungin Approved in Europe for Treatment and Prevention of Fungal Infections

TOKYO -- May 7, 2008 -- The antifungal micafungin sodium (Mycamine) has been approved in Europe for the treatment of various Candida infections.

The indications for adults, adolescents 16 years of age and older, and the elderly are treatment of invasive candidiasis, treatment of oesophageal candidiasis in patients for whom intravenous therapy is appropriate, and prophylaxis of Candida infection in patients undergoing allogeneic haematopoietic stem cell transplantation or patients who are expected to have neutropenia (absolute neutrophil count <500 cells/mcL) for 10 or more days.

For children (including neonates) and adolescents younger than 16 years of age, micafungin is indicated for treatment of invasive candidiasis and prophylaxis of Candida infection in patients undergoing allogeneic haematopoietic stem cell transplantation or patients who are expected to have neutropenia (absolute neutrophil count <500 cells/mcL) for 10 or more days

Micafungin is expected to launch first in the United Kingdom and then across Europe shortly thereafter. The antifungal has been available in Japan since December (Funguard for Infusion), where it has established its therapeutic efficacy against fungal infections caused by Aspergillus and Candida and safety through all therapeutic results. Micafungin has been available in the United States since May 2005 and is now indicated for treatment of patients with candidaemia, acute disseminated candidiasis, Candida peritonitis, and abscesses; treatment of patients with oesophageal candidiasis; and prophylaxis of Candida infections in patients undergoing haematopoietic stem cell transplantation.

SOURCE: Astellas Pharma Inc.

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