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Cryoablation of Kidney Tumour Appears Successful With Few Complications: Presented at SIR By Ed Susman WASHINGTON, DC -- March 25, 2008 -- Treatment of kidney tumours by cryoablation successfully destroys the lesions without causing major complications for the patients, researchers reported here at the Society of Interventional Radiology [SIR] 33rd Annual Scientific Meeting. Percutaneous cryoablation using computed tomography (CT) guidance is a viable treatment option for selected small renal cell tumours and offers good short-term results and no major complications, said investigator Mark A. Gibson, MD, Resident in Diagnostic Radiology, Eastern Virginia Medical School, Norfolk, Virginia. In the retrospective study, Dr. Gibson and colleagues identified 14 men and 13 women who underwent a total of 30 cryoablation procedures to eliminate tumours in the kidneys. The average age of the patients was 67 years. "The cases selected for cryoablation were in predominantly high-risk surgical patients with small tumours felt [to be] amenable to percutaneous therapy," Dr. Gibson said in his featured poster presentation on March 18. Of the 27 tumours treated, 19 were renal cell carcinoma, 5 other tumours were also malignant or were premalignant, and 3 tumours were benign lesions, Dr. Gibson said. Patients were placed under conscious sedation or general anaesthesia while doctors guided catheters to the long axis of the tumour using 1 to 4 probes for each patient so that the ice ball would grow medially into the tumour. The tumours were frozen at a temperature of -100 Celsius to -120 Celsius for 10 minutes; thawing was permitted for 8 minutes and then the tumours were frozen again for another 10 minutes. When deemed necessary, doctors injected percutaneously dextrose 5% or saline solution to create a buffer between vital structures, such as the bowel. Three tumours recurred and were subsequently successfully retreated with cryoablation, said Dr. Gibson. Mean time to recurrence in these 3 cases was 10 months. He said that technical success in freezing the tumours was 100%. All patients underwent CT scans or magnetic resonance imaging that documented a renal mass. Percutaneous biopsies were performed prior to cryotherapy. [Presentation title: CT Guided Percutaneous Cryoablation of Renal Tumours. Abstract 329] E-mail this page to a friend or colleague! To print, use this version