Dilute Hypochlorite Solution Wipes Away Indoor Allergens: Presented at ACAAI
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Dilute Hypochlorite Solution Wipes Away Indoor Allergens: Presented at ACAAI

By Carole Bullock

DALLAS, TX -- November 13, 2007 -- Routine treatment of hard surfaces, fabric, and carpet with dilute hypochlorite solution reduced exposure to allergenic material in the indoor environment, researchers reported here at the American College of Allergy, Asthma and Immunology (ACAAI) annual scientific meeting.

"Methods of allergen reduction in the home have long been an area of focus for control of symptoms in allergies and asthma. Specific practices such as pet removal or dust elimination are frequently recommended to allergy sufferers," said Gregory Pendell, MD, Fellow, University of Missouri-Kansas City, Kansas City, Missouri, United States, who reported the research in a poster presentation on November 11.

"Our goal was to determine if a dilute hypochlorite solution would denature the allergens and reduce asthmatic symptoms," said Dr. Pendell.

Twenty-five homes containing at least 3 persons and at least 1 asthmatic child were enrolled in the study. Families were given either distilled water spray (the control group) or dilute hypochlorite spray in identical bottles and asked to spray designated areas 3 times a week. "The solution is so dilute that it doesn't smell any different than the control," Dr. Pendell noted.

Researchers collected dust samples from furniture, carpet, and bedding on 4 different occasions for 6 weeks. "Dust samples were taken both before and after spraying the interior of the home. Samples were taken from equal areas, but not from the same place pre- and post-spraying," he said.

Dust was analysed by enzyme immunoassay for antigenic material related to 5 separate taxa, including Aspergillus, Alternaria, dog, cat, and dust mite. Statistical comparisons were made between pre- and post-spray dust allergen levels.

Reductions in dust allergen levels were seen in 4 of the 5 allergens tested and were significant at the 95% confidence level, said Dr. Pendell.

"Our study shows that routine treatment of home interiors including hard surfaces, fabric, and carpet with dilute hypochlorite solution can reduce exposure to allergenic material in the indoor environment," he said.

[Presentation title: Dilute Hypochlorite Solution for Reducing Home Allergen Exposure. Abstract P68]

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