Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

Breastfed Infants Gain Future Heart-Health Benefits: Presented at AHA By Carole Bullock ORLANDO, FL -- November 6, 2007 -- Breastfed babies grow up to have higher high-density lipoprotein (HDL) cholesterol -- and tend to be slimmer -- than their bottle-fed counterparts, according to the Framingham Third Generation Study. The study's findings were reported here on November 5 at the American Heart Association (AHA) 2007 Scientific Sessions. This study stands out from other breastfeeding studies because it focuses on adult risk factors and adjusts for confounding factors among mothers and participants, said study author Nisha Parikh, MD, MPH, Cardiovascular Fellow, Beth Israel Deaconess Medical Center, Boston, Massachusetts. The Third-Generation participants had at least one parent in the Framingham Offspring Study. Overall 26% of the Third-Generation offspring who responded to a mailed questionnaire reported that they had been breastfed. Breastfed offspring had an adult-adjusted mean body mass index (BMI) of 26.1 kg/m2, compared with 26.9 kg/m2 for bottle-fed (P =.04). Adult HDL-C levels were higher among breastfed compared with bottle-fed offspring. The adjusted mean HDL was 56.6 mg/dL for breastfed offspring and 53.7 mg/dL for bottle-fed, in multivariable-adjusted models (P =.01). The 962 Framingham Third Generation participants (mean age = 41 years; 54% women) were surveyed on history of breastfeeding and risk factors for cardiovascular disease (CVD) -- BMI, blood cholesterol, blood pressure, and C reactive protein. The analysis adjusted for age, sex, hypertension medications, lipid treatment, smoking, birth order, oral contraceptives, hormone replacement, physical activity, and education. Other covariates were maternal smoking, maternal education, and maternal adiposity, defined as BMI normal (<25), overweight (>25 to <30), and obese (>=30 kg/m2). Low HDL was defined as <50 mg/dL (women) and <40 mg/dL (men). Adiposity categories were defined by BMI normal (<25), overweight (>25 to <30) and obese (>=30 kg/m2). Breastfeeding was not linked to the other adult CVD risk factors examined in the study. After adjustment for BMI, the association between breastfeeding and HDL was attenuated (P =.09). Associations between breastfeeding and BMI appear to mediate most of this association with HDL-C, the investigators reported. "This is an observational study; however, it does show that it may be important to attack CVD earlier in life, instead of waiting until a person is in their 40s," Dr. Parikh said in an interview. The study may also point to a mechanism at play: breast milk contains adipokines, a group of signaling proteins secreted by adipose tissue that may modify appetite, insulin resistance, and atherosclerosis. "More studies are needed to understand the mechanism and metabolic actions of adipokines and other factors that may be related to cardiovascular disease in early life." [Presentation title: Gender and Ethnic Factors in CHD: Abstract 3498] E-mail this page to a friend or colleague! To print, use this version