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Colorectal Cancer Screening by Primary Colonoscopy Shows Promise in the Workplace: Presented at UEGW By Jill Stein PARIS, FRANCE -- October 31, 2007 -- Investigators are reporting early favorable results using primary colonoscopy for colorectal cancer screening (CRC). Caroline Khalid-de Bakker, MD, Gastroenterologist, University Hospital, Maastricht, Netherlands, and colleagues reported the results of primary colonoscopy for CRC screening at their institution on October 30 at the 15th United European Gastroenterology Week (UEGW). Individuals targeted for the program, who ranged from 50 to 65 years of age, were contacted by a letter with an information brochure on screening colonoscopy. Open information sessions were also held to recruit individuals for CRC screening. Colonoscopies were performed by experienced endoscopists using conscious sedation. Individuals who had severe comorbidities, had undergone a colonoscopy within the prior 5 years, or had recent GI symptoms were ineligible. Overall, 987 employees were invited to participate. So far, 328 colonoscopies have been performed, with a mean duration of 18.6 ± 11.8 min. for caecal intubation and 35.4 ± 15.1 min. for total examination. The caecal intubation rate was 89%. Caecum was reached more often in men than in women (93.9% versus 81.6%, P <.05). There were no major complications. Minor events occurred in 37.3% of examinations and involved mostly mild hypoxia, defined as 02 sat less than 90. Adenomas were detected in 23.5% of participants, and 25.6% of those had lesions only located proximal to the flexura lienalis, out of the reach for sigmoidoscopy. The miss rate would have been 22.6% of those with advanced adenomas. One month after the colonoscopy, bowel preparation and colonoscopy were rated as uncomfortable by 77% and 33.9%, respectively. However, 97.3% of participants were prepared to repeat the colonoscopy in the future, if needed. The investigators said that early results suggest that the work-based CRC screening is feasible, well accepted, and has a high diagnostic yield. [Presentation Title: Primary Colonoscopy for Colorectal Cancer. Abstract G-307] E-mail this page to a friend or colleague! To print, use this version