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Inflammatory Bowel Disease May Boost Risk of Bone Problems: Presented at UEGW By Jill Stein PARIS, FRANCE -- October 30, 2007 -- Newly diagnosed patients with inflammatory bowel disease (IBD) may be at increased risk of osteoporosis or osteopaenia, according to findings presented here at the 15th United European Gastroenterology Week (UEGW). C. R. DeSouza, MD, Consultant Gastroenterologist, Chase Farm Hospital, Enfield, United Kingdom, and coworkers presented the results of bone density scanning of the hip and lumbar spine in 26 men and women in a presentation on October 29. All patients were aged between 18 and 45 years and had newly diagnosed IBD, a body mass index greater than 21 kg/m2, normal bone chemistry, and a recent histological diagnosis of Crohn's disease, ulcerative colitis, or colitis of undetermined origin. "Patients with inflammatory bowel disease who have established risk factors for osteoporosis such as corticosteroid use, postmenopausal prior fractures, bowel resection, malabsorption, low body mass index, and smoking are screened with bone densitometry," D. DeSouza noted. "At-risk patients are started on treatment and are followed up with repeat bone densitometry scans. The present study was undertaken to determine if patients with newly diagnosed IBD in a district general hospital without any specific risk factors for osteoporosis were at high risk of osteoporosis. Results showed that 17 patients had normal bone densitometry at both the hip and lumbar spine. However, six patients had osteopaenia and three patients had osteoporosis. Dr. DeSouza said that the study is too small to allow a determination of which type of IBD or which disease distribution is more likely to have osteoporosis. These early results suggest that IBD may be a risk factor for osteoporosis, he added, and the data need to be corroborated in larger trials. [Presentation title: High Probability of Osteoporosis in Newly Diagnosed Patients With Inflammatory Bowel Disease. Abstract G-248] E-mail this page to a friend or colleague! To print, use this version