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Laparoscopic Cholecystectomy for Biliary Dyskinesia in Children Provides Durable Symptom Relief: Presented at AAP By Nora Steiner Mealy SAN FRANCISCO, CA -- October 29, 2007 -- Laparoscopic cholecystectomy was found to relieve symptoms in children with biliary dyskinesia, according to study findings presented here at the American Academy of Pediatrics National Conference and Exhibition (AAP). The study involved 23 children with a median age of 14 years (range 7-18 years) with chronic abdominal pain, no gallstones seen on ultrasonography, and an abnormal cholecystokinin hepatoiminodiacetic acid (CCK-HIDA ) scan with mean ejection fraction of 17% (SD 8%). Common preoperative complaints were right upper quadrant or epigastric pain (78%), nausea (52%), vomiting (43%), and generalised abdominal pain (22%) with a median duration of 3 months and a range of 1 month to 2.5 years). At the first visit following laparoscopic cholecystectomy, 54% reported complete resolution of symptoms, 33% improved markedly, and 13% had no change. Longer-term follow-up with a symptom questionnaire was completed by 70% of study participants after a median postoperative period of 2.7 years (range, 6 months-6 years): in the month preceding the questionnaire, 63% reported that they had no abdominal pain, 87% had no vomiting, and 69% had no nausea. Seven percent had no improvement in symptoms, noted study presenter Ramanath N. Haricharan, MBBS, MPH, Assistant Professor of Surgery, Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, Alabama, United States. During the same time period, 41 additional children had similar characteristics, including an abnormal CCK-HIDA scan, but they did not undergo laparoscopic cholecystectomy. Symptoms questionnaires were also sent to these children, but because the researchers received only nine responses, they were unable to compare them to the study group. "Although school absences were frequent prior to the procedure due to abdominal complaints, parents reported in long-term follow-up that 90% of the children had not missed any school in the preceding month," Haricharan noted. Laparoscopic cholecystectomy is effective in providing both short-term and long-term improvement of symptoms in children with chronic abdominal pain and abnormal ejection fraction on CCK-HIDA scan, the study authors concluded. [Presentation title: Laparoscopic Cholecystectomy for Biliary Dyskinesia in Children Provides Durable Symptom Relief. Abstract 715] E-mail this page to a friend or colleague! To print, use this version