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AAN: Botox (Botulinum Toxin Type A) Shows Promise In Treating Severe Headaches DENVER, CO -- April 18, 2002 -- Speaking today at the Annual Meeting of the American Academy of Neurology in Denver, Dr. Alexander Mauskop reported that long-term headache sufferers receiving Botox (botulinum toxin Type A) had superior symptom relief and minimal or no treatment side effects. Patients who had had severe headache for as long as 20 years and who had failed to respond to multiple treatments experienced relief ranging from complete elimination of headaches to partial decrease in frequency and/or intensity of pain. A review of 80 patients who received four or more treatments with Botox at The New York Headache Center indicated that, in addition to relief from migraine and chronic tension-type headache, patients reported that their abortive medications worked better than usual and need for medications was reduced. The side effect profile of Botox is very favorable, according to Dr. Mauskop. While drooping of the eyelids, mild neck weakness or even worsening of neck pain is possible, though very rare and of relatively brief duration, the benefits outweigh any disadvantages for most patients. Botox has no negative effect on mood, thinking, weight, or energy level that can occur with other prophylactic drugs. It is a simple and brief procedure that takes about 10 minutes in the doctor's office Dr. Mauskop noted that patients continued to obtain relief even after multiple treatments over long periods of time and after failure of most other therapies. Botox is thought to work in part by causing long-term relaxation of muscles and injection site selection is based on pain and trigger point distribution. In many patients, there was a clear correlation between the return of muscle strength and the return of headaches. Botox has been on the market in the US for the past 12 years and is currently approved by the FDA for blepharospasm, torticollis and to treat frown lines. The New York Headache Center is currently enrolling patients in two large clinical trials that may lead to approval of Botox for the treatment of chronic and episodic migraine headaches. The New York Headache Center, located in Manhattan, is one of the country's leading centers for research and treatment of migraine and all other types of headache. SOURCE New York Headache Center E-mail this page to a friend or colleague! To print, use this version