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AEC: Carbofilm Coronary Stent Shows Promise in Early Trials By Koren Capozza Special to DG News SCOTTSDALE, AZ -- February 13, 2002 -- Results from an Italian study of a new carbon/stainless steel coronary stent suggest that the technology can be a safe alternative for patients who are unable to receive antiplatelet therapy. The turbostatic carbon model, called Carbostent™, from Sorin, is coated with Carbofilm™, a thin film designed to improve biocompatibility. This new model also addresses three common complications associated with stenting: thrombosis, restenosis and arterial injury. The findings were presented here today at the 15th Annual Endovascular Congress. Between September 2000 and July 2001, the researchers enrolled 143 patients, who were between the ages of 35 and 86 years and had coronary lesions, to receive the Carbostent plus ticlopidine treatment. Twenty-six of the patients could not receive antiplatelet therapy and received only aspirin pre-treatment -- 16 of these patients because they had potential contraindication to ticlopidine, an antiplatelet drug, and the remainder because they were part of another study. Another group of 73 patients who had not been previously treated with ticlopidine were pre-treated with the drug. A total of 143 patients received 163 stents. Results show the Carbofilm-coated stent was successful in addressing the lesions in 99 percent of patients. All but two of the patients were asymptomatic at one-month follow up. The stent appeared to be equally effective in patients regardless of prior drug therapy. Preliminary results suggest that the stent may also have successful applications beyond the coronary artery and further study should investigate its broader use, said lead author Dr. Antonio Benassi of the Hesperia Hospital in Modena Itlay. "Maybe we can also find an application in the peripheral circulation," he added. Nearly 80 percent of blood vessel reconstruction procedures now involve stent technology. E-mail this page to a friend or colleague! To print, use this version