Selenium May Help Prevent Prostate Cancer
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Selenium May Help Prevent Prostate Cancer

STANFORD, CA -- November 30, 2001 -- Men with low blood levels of selenium -- a trace element supplied in certain foods and supplements -- are four to five times more likely to contract prostate cancer.
According to a federally sponsored study published in the Dec. 1 issue of the Journal of Urology, the findings confirm that higher blood levels of selenium are associated with lower risks of prostate cancer.

James D. Brooks, MD, assistant professor of urology at Stanford University and lead author of a paper, said, "Perhaps the most interesting finding of this study was that blood selenium levels decreased with age -- a fact not previously known. Furthermore, this study showed there was a direct connection between selenium and prostate cancer -- older men with higher levels of selenium were at lower risk."

The study suggests that eating more selenium-rich foods, such as Brazil nuts and tuna, or taking a dietary supplement, may reduce the risk of prostate cancer. Brooks said further study is needed to determine if supplements will actually raise selenium levels in the blood.

Nevertheless, the researchers concluded that the results support the hypothesis that supplemental selenium may reduce the risk of prostate cancer. Because selenium in blood decreases with patient age, supplementation may be beneficial to older men.

Brooks’ study included 52 men with prostate cancer and 96 men without the disease. The median age was just under 69. The men’s health histories and medical risks have been tracked for many years as part of the federally sponsored Baltimore Longitudinal Study of Aging.

Dr. Brooks was joined in the study by scientists at the Laboratory of Clinical Investigation of the National Institute on Aging, and Johns Hopkins University School of Medicine. The project was supported by a grant from the National Institute on Aging.

Prostate cancer is the No. 1 form of cancer affecting men, and a leading cause of cancer deaths among men, according to the American Cancer Society.

A large study is now under way at Stanford and other major medical centers to test whether supplements will reduce prostate cancer rates.

SOURCE: Stanford University.

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