Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

AHA: Diet and Exercise Alone Shown to Lower C-Reactive Protein By Bruce Wilson Special to DG News ANAHEIM, CA -- November 14, 2001 -- High sensitivity C-reactive protein (hs-CRP) can be effectively reduced by non-pharmacologic therapy using a structured program of exercise training and diet. This finding was presented at this year’s American Heart Association (AHA) meeting. Until now, only statin therapy has been shown to effectively reduce hs-CRP via mechanisms that are unrelated to lowering LDL cholesterol, noted Dr. Carl Lavie and researchers from the Alton Ochsner Medical Center in New Orleans, Louisiana, United States. Hs-CRP, a marker of low level inflammation, has been found to be a strong predictor of myocardial infarction and stroke in men and women, as well as subsequent clinical events in patients following major cardiac events. Researchers sought to determine whether a structured program involving a low-fat, Mediterranean diet and a supervised, three-times weekly exercise program for three months could have a positive effect on hs-CRP values. The study assessed hs-CRP and traditional cardiac risk factors in 65 coronary artery disease (CAD) patients following PTCA and MI. The patients, who had a mean age of 64, plus or minus 10 years, were measured at baseline and after completion of three months of Phase II cardiac rehabilitation and exercise training. Values of hs-CRP dropped 31 percent after the three months - from 4.2 mg/L (5th quintile of CAD risk) at baseline to 2.9 mg/L (4th quintile of CAD risk) (p<0.004), the researchers found. In addition, body fat was reduced by 5 percent (from 26.1 percent to 24.8 percent, p <0.01) and exercise capacity improved 36 percent (5.5 to 7.5 METs, p < 0.02). However, there were no significant changes in serum lipids, including total cholesterol, HDL, LDL or triglycerides (baseline values 176 mg/dL, 42 mg/dL, 103 mg/dL, and 161 mg/dL respectively). Noting that the changes in hs-CRP values occurred independent of lipid modulation, Dr. Lavie concluded that an approach involving low fat diet and progressive exercise training can augment pharmacologic strategies in altering inflammatory markers in CAD. E-mail this page to a friend or colleague! To print, use this version