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FDA Approves Tequin (Gatifloxacin) For Short Course Treatment of Acute Bacterial Exacerbation Of Chronic Bronchitis PRINCETON, NJ -- November 7, 2001 -- Bristol-Myers Squibb Company has announced that Tequin® (gatifloxacin), a broad-spectrum fluoroquinolone antibiotic, has been approved by the U.S. Food and Drug Administration as a short-course (five-day) regimen in the treatment of acute bacterial exacerbation of chronic bronchitis (ABECB). Tequin is already approved for ABECB, acute sinusitis and community-acquired pneumonia. "We are very impressed that, in our research, Tequin has been shown to be effective in treating acute exacerbation of chronic bronchitis in just five days," commented Mark H. Gotfried, M.D., FCCP, Pulmonary Associates, Phoenix, Arizona. Dr. Gotfried spearheaded the research that demonstrated that a short-course (five-day) regimen of Tequin 400mg QD for ABECB was found to be comparable in clinical cure and microbiologic eradication rates to a standard seven-day regimen of Tequin. The two most common pathogens that cause ABECB are S. pneumoniae and Haemophilus influenzae. The activity of Tequin against S. pneumoniae and Haemophilus influenzae makes it an ideal agent for short course treatment of acute exacerbation of chronic bronchitis. In addition, Tequin (gatifloxacin) was well tolerated in the study. The study was published in the January 2001 issue of Clinical Therapeutics. SOURCE: Bristol-Myers Squibb Company E-mail this page to a friend or colleague! To print, use this version