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DG DISPATCH - ACAAI: Fluticasone Propionate Eases Sinus Pain Associated With Allergic Rhinitis By Jill Stein Special to DG News SEATTLE, WA -- November 6, 2000 -- Fluticasone propionate aqueous nasal spray presents an effective treatment for sinus pain and pressure associated with nasal congestion in patients with allergic rhinitis, according to data presented at the annual meeting of the American College of Asthma, Allergy, and Immunology. A group from the Southwest Allergy and Asthma Research Center in San Antonio, Texas, assessed the effects of two weeks’ treatment with a once -daily 200 mcg dose of fluticasone propionate nasal spray or placebo on sinus pain and pressure and nasal congestion in 195 patients with seasonal or perennial allergic rhinitis. In all patients, the presence of rhinitis had been confirmed by skin test results, a review of their medical histories for the past two seasons/years, and physical examination. Patients were 12 years of age or older. "Sinus pain and pressure associated with nasal congestion are troublesome but not well characterized symptoms of rhinitis," Dr. Bruce G. Martin, an allergist, said. Results showed that the intranasal corticosteroid regimen was significantly more effective than placebo in decreasing sinus pain and pressure scores over the entire two-week treatment period. Fluticasone propionate nasal spray also provided significantly greater improvements in symptoms of nasal congestion over the entire two-week treatment period. The medication was well tolerated with an adverse event profile similar to that of placebo. Intranasal corticosteroids and antihistamines are widely used for the treatment of seasonal and perennial allergic rhinitis. Intranasal corticosteroids are potent and well-tolerated and are recognized as the most effective medication class for controlling symptoms of allergic rhinitis. Fluticasone propionate is indicated for the nasal symptoms of seasonal allergic rhinitis, perennial allergic rhinitis, and perenial non-allergic rhinitis in adults and children over four years of age. E-mail this page to a friend or colleague! To print, use this version