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Cystic Fibrosis Patients Showed Significant Improvement With HP-3 BOXFORD, MA. -- December 13, 1999 -- Milkhaus Laboratory, Inc. announced that a Phase II clinical trial of its product, HP-3, was successful in treating patients with cystic fibrosis. The results showed significant improvement in pulmonary function and an increase in sputum clearance. Cystic fibrosis is a chronic, inherited disease of the exocrine glands that affects children and young adults. Thick mucus builds up in the lungs which severely limits pulmonary function and the ability to carry out normal activities of living. Chronic lung infections are common and damage to lung tissue occurs as a result of inflammation and chronic oxygen deprivation. There is no effective treatment for the disease. Products currently available offer only nominal improvements in symptoms for the 35,000 patients in the U.S. Commenting on this trial, the Company's CEO, Dr. John McMichael, said: "Our cystic fibrosis trial was one of three we conducted using HP-3 in patients with diseases involving respiratory distress caused by sputum or scar tissue blocking the airways. The other trials were in chronic bronchitis and chronic obstructive pulmonary disease, or COPD. In all three, HP-3 increased sputum expectoration and significantly improved pulmonary function. We believe it evokes such responses through a mechanism common to all three disease categories. As a result, the product has very broad potential utility in relieving the debilitating symptoms of respiratory distress which afflict more than 15 million people in the U.S. Furthermore, results suggest that it does so safely and without the need to limit the use of other medications." E-mail this page to a friend or colleague! To print, use this version