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DG DISPATCH - RSNA: Radiofrequency Ablation Effective For Breast Cancer Liver Metastases By Lara Pullen Special to DG News CHICAGO, IL -- December 1, 1999 -- There is no established treatment for breast cancer metastases to the liver. A recent study, however, indicates that radiofrequency (RF) ablation is a safe and simple procedure that is an effective treatment for these local hepatic metastases. At the 85th Annual Meeting of the Radiological Society of North America, in Chicago, IL, Dr. Tito Livraghi, of Vimercate Hospital, in Italy presented the results of a study designed to evaluate the efficacy of RF ablation in breast cancer liver metastases. The study consisted of 15 lesions in 10 patients (mean age of 51) who were treated at Vimercate Hospital. Eight of these patients had progressive metastatic disease after chemotherapy, while two patients had refused chemotherapy and presented with hepatic metastases only. Patients underwent ultrasound-guided RF ablation using 17-gauge, internally cooled electrodes. Following RF ablation, therapeutic efficacy was evaluated with biphasic helical computed tomography (CT) performed at four-month intervals. Follow-up ranged from four to 30 months. Complete necrosis was obtained in 14 out of 15 lesions (93 percent). Follow-up imaging studies were unable to detect a recurrence in any of the 14 lesions. Four patients have remained disease free, five developed new hepatic and/or extra-hepatic metastases, and one died with diffuse metastases. RF ablation resulted in no complications. E-mail this page to a friend or colleague! To print, use this version