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| | | ![]() ACAAI: Astelin Spray Effective In Treating Perennial Nonallergic Rhinitis CHICAGO, IL -- November 19, 1999 -- Results of a randomized, double-blind clinical trial, released this week at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Meeting, demonstrated that Astelin® (azelestine HCl) Nasal Spray, 137 mcg, an antihistamine available in the United States for treating seasonal allergic rhinitis, is effective in the treatment of vasomotor rhinitis (VMR), a common form of nonallergic rhinitis. Although hay fever-seasonal allergic rhinitis-is the condition most people are familiar with, there are different forms of rhinitis. Seasonal allergic rhinitis (SAR) is caused by allergens such as pollens and mold spores. Perennial nonallergic rhinitis or vasomotor rhinitis (VMR) is associated with symptoms similar to allergic rhinitis (runny nose, sneezing, postnasal drip, and nasal congestion) that are exacerbated by triggers such as cold air, damp weather, perfume or chemical odors, spicy food, and alcohol. The study compared azelastine hydrochloride-marketed as Astelin Nasal Spray-to placebo in 223 patients with VMR. The results presented at the American College of Allergy, Asthma and Immunology Annual Meeting found that Astelin Nasal Spray significantly reduced the total vasomotor rhinitis symptom scores over the 21-day treatment period when compared to placebo. The most commonly reported adverse events were bitter taste, headache, and dysaesthesia, and more than 90 percent of the patients completed the study. "These findings will be especially pertinent to individuals who have not experienced relief for nasal symptoms," said Phil Lieberman, MD, an investigator for the clinical trial. "In some instances, the failure to relieve symptoms may be related to the fact that allergies per se are not actually causing the problem. Many people with nasal allergy symptoms are not actually allergic. Now we have a medication for both allergic and non-allergic triggered nasal symptoms, hopefully many of these patients can be successfully treated."
Related Link: Astelin® (azelestine HCl) Nasal Spray.
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