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DG DISPATCH - HEADACHE: Study Sheds Light On Link Between Hormones And Migraine With Aura By Cameron Johnston Special to DG News BARCELONA, SPAIN -- June 28, 1999 -- An Italian study has shown just how profoundly a woman’s migraines can be affected by her hormonal cycle. While the results probably won’t result in any clinical breakthroughs, they might give the women and their doctors some reassurance as to why their headache can be so unpredictable and so maddening. The study compared 100 women with 200 age-matched controls at Pavia University’s Centre for Adaptive Disorders and Headache, and Parma University’s department of neurology. These results were presented at the ninth congress of the International Headache Society meeting, in Barcelona, Spain. The study’s findings show, among other things, that women who have migraines without aura are more likely to have irregular menstrual periods, if they have them at all, than women who have migraines with aura. By contrast, pre-menstrual syndrome was six times more common in women who had migraines with aura compared with women who did not have migraines with aura. It has been known for some years that a many women’s migraine headache fluctuate in direct relationship to their hormonal cycles, the investigators said. “This data show just how different the influence can be for women who have migraine with aura compared to migraine without aura. The two forms of migraine could be due to a different -- and as yet unknown sensitivity to the changes in the female sex hormones.” The study also found that women who have migraine with aura only have one-third as many headache attacks during their periods than women who have migraines without aura. In contrast, women who take oral contraceptives are also twice as likely to have migraines with aura. E-mail this page to a friend or colleague! To print, use this version