Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

DG DISPATCH - ECFC: CF Patients Have Higher Immune Responses To C. Albicans By Martin Goldman Special to DG News THE HAGUE, THE NETHERLANDS -- June 14, 1999 -- Patients with cystic fibrosis (CF) have significantly higher immune responses to Candida albicans compared to individuals without the condition as a response to colonisation of the respiratory tract by this yeast. Dr. L Maiz, of the pneumonology department, Ramon Y. Cajal Hospital, Madrid, Spain, and her colleagues carried out a prospective six-year evaluation, to find the importance of C. albicans and the immune response this produced in patients with cystic fibrosis. The results were presented at the European Cystic Fibrosis Congress. A total of 76 cystic fibrosis patients were evaluated over the six-year period and 1,239 samples of respiratory secretions were cultivated for the presence of bacteria. In 66 of these patients, 400 serum samples obtained every three to four months were analysed during the last three years of the study. The researchers evaluated the samples for total IgE, IgG, IgA and IgM against C. albicans using the ELISA assay. Of the patients studied, 588 respiratory secretion samples were positive for C. albicans (87.9 percent); 90.8 percent presented some kind of immune response against C. albicans. There was a significant correlation between the degree of colonisation and the IgG and IgA against C. albicans and this had an R value of not less than 0.6. The researchers concluded that patients with cystic fibrosis present significantly higher immune responses to C. albicans compared to normal subjects as a response to colonisation of the respiratory tract. Pulmonary deterioration of the patients facilitates C. albicans colonisation and the degree of colonisation is paralleled by the immune response. E-mail this page to a friend or colleague! To print, use this version