Unregistered User If this is not your name, click here.
		Contact Us | Order Now | Journals | Bookstore | Register a colleague
	Select a ChannelAcneAIDS and HIVAllergy OtherAlzheimer'sAnaesthesiology OtherAngina Pectoris/MIAnxietyArthritis OtherAsthmaBack PainBacterial InfectionsBladder CancerBone Marrow TransplantationBreast CancerCardiology OtherCataractCell TransplantationCervical CancerCholesterol/Lipid disordersCirrhosisClinical PharmacologyColorectal CancerCongestive Heart FailureContact DermatitisContraceptionCOPDCystic FibrosisDental and Oral DisordersDepressionDermatology OtherDiabetesDialysisEating DisordersElbowEmergency MedicineEndocrinology OtherEpilepsyErectile DysfunctionFibromyalgiaGastro OtherGeneticsGenitourinary OtherGeriatricsGERD/GastritisGlaucomaH. Pylori/UlcerHaematology OtherHair LossHeadachesHepa/Biliary OtherHepatitisHipHRTHypertensionIBDImmunologyInfectious OtherInfertilityIntensive CareIrritable Bowel SyndromeKneeLeukemiasLiver CancerLung CancerLupusLymphomasMelanomaMenopauseMultiple Sclerosis Nephrology OtherNeurologic OtherNutritional / Metabolic OtherOb/Gyn OtherObesityOncology OtherOphth. OtherOphthalmic SurgeryOrgan TransplantationOrthopaedics OtherOsteoarthritisOsteoporosisOtitisOtorhino. OtherOvarian CancerPaediatricsPainPancreatic CancerParkinson'sPregnancyProstate CancerPsychiatry OtherPulmonary OtherRadiologyRenal CancerRenal FailureRespiratory InfectionsRheumatoid arthritisRheumatology OtherRhinitisSchizophreniaShoulderSleep ApnoeaSleep DisordersSpineStrokeSTDsSurgeryThyroid DisordersTransfusionTransplant Surgery OtherTraumaUrinary IncontinenceUrinary tract infectionsVaccinologyVascular DisordersViral Infections

SEARCH   News Bookstore Medline The Web Meetings & Congresses Complete Doctor's Guide    EXPLORE :    All News   All Webcasts   All Cases   All Meetings & Congresses   All Medical Resources New drugs / indications English Dictionary Medical Dictionary Thesaurus Warning | Privacy | Awards  Favourite Journals  Click here to choose your favourite journals  Favourite Sites  Click here to choose your favourite sites  Languages  Select languageEnglishFrançais

PSA Value 2 Years Post-Radiation Predicts Long-Term Survival in Prostate Cancer Patients FAIRFAX, Va -- December 3, 2009 -- Patients with prostate cancer and a prostate-specific antigen (PSA) value of <=1.5 at 2 years after external beam radiation therapy (EBRT) are less likely to have a cancer recurrence and cancer-related death, according to a study published in the December 1 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology (ASTRO). After a successful course of EBRT, PSA levels should decline gradually over the following 18 to 24 months. A continued rise in PSA can indicate relapsing disease. Prior studies have attempted to categorise PSA response patterns after treatment to identify patients with an increased likelihood of relapsing earlier; however, most did not use a fixed point after treatment to predict outcomes. Researchers at the Memorial Sloan-Kettering Cancer Center, New York, New York, sought to determine the significance of a patient’s reaching a certain PSA level at a specific point in time after EBRT. The study authors found that patients with a PSA value of <=1.5 at 2 years had a 2.4% incidence of distant metastases at 5 years after treatment and a 7.9% incidence at 10 years. Patients with a PSA value >1.5 experienced a significantly higher rate of metastases at 5 and 10 years after treatment (10% and 17.5%, respectively). “In the past, patients with a relapsing cancer after receiving radiation were not identified until several years after treatment, and at that point it may be too late to effectively salvage their recurrence,” said Michael Zelefsky, MD, lead author of the study, Memorial Sloan-Kettering Cancer Center, New York, New York. “If we can catch these future instances of cancer recurrence earlier in prostate cancer patients, then we have a much higher chance of reducing the mortality associated with the cancer.” SOURCE: International Journal of Radiation Oncology*Biology*Physics E-mail this page to a friend or colleague! To print, use this version