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Diagnostic Imaging May Help Identify Severe Cases of Influenza A(H1N1) LEESBURG, Va -- October 13, 2009 -- Researchers at the National Institutes of Health (NIH), Bethesda, Maryland have found that imaging can now be used as a tool for identifying severe cases of influenza A(H1N1). In addition, diagnostic imaging may play a key role in understanding the pathogenesis of the virus, possibly leading to earlier diagnoses of severe cases in the future. The study is published online today in the American Journal of Roentgenology and will be published in the December print issue of the journal. Imaging revealed a severe case of H1N1 after a patient had tested negative using a nasal swab rapid antigen test. Radiography showed peripheral lung opacities, and computed tomography (CT) revealed peripheral ground-glass opacities. Both findings raised suspicion of H1N1 and reports revealed that the patient later died from a severe case of H1N1. “The role of radiologic imaging in epidemic detection and response is evolving, with imaging being used as a tool for identifying severe cases,” said lead author Daniel J. Mollura, MD, Johns Hopkins, Baltimore, Maryland. “At the Center for Infectious Disease Imaging at the NIH, the study of influenza is a priority with a focus on achieving early diagnosis and understanding its pathogenesis.” “Early CT may help clinicians recognise cases of severe influenza and monitor response to treatment. More cases will certainly need to be analysed and compared in the future, but this is a promising early result,” said Dr. Mollura. SOURCE: American Roentgen Ray Society E-mail this page to a friend or colleague! To print, use this version